New Publication in ISME Journal and in Environmental Research
High cell densities favor lysogeny: induction of an H20 prophage is repressed by quorum sensing and enhances biofilm formation in Vibrio anguillarum
Demeng Tan, Mads Frederik Hansen, Luís Nunes de Carvalho, Henriette Lyng Røder, Mette Burmølle, Mathias Middelboe and Sine Lo Svenningsen
The ISME Journal (2020)
Temperate φH20-like phages are repeatedly identified at geographically distinct areas as free phage particles or as prophages of the fish pathogen Vibrio anguillarum. We studied mutants of a lysogenic isolate of V. anguillarum locked in the quorum-sensing regulatory modes of low (ΔvanT) and high (ΔvanO) cell densities by in-frame deletion of key regulators of the quorum-sensing pathway. Remarkably, we find that induction of the H20-like prophage is controlled by the quorum-sensing state of the host, with an eightfold increase in phage particles per cell in high-cell-density cultures of the quorum-sensing-deficient ΔvanT mutant.
More news in Danish on the study can be found HERE >>
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The T-shirt microbiome is distinct between individuals and shaped by washing and fabric type
Eva Baggesgaard Sterndorff, Jakob Russel, Jonas Jakobsen, Martin Steen Mortensen, Klaus Gori, Jakob Herschend and Mette Burmølle
Environmental Research, Volume 185, June 2020
Short abstract
Activity of the microbial population in clothing causes unpleasant odor and textile deterioration. However, little is known about how the textile microbial community is shaped. In this study, we developed a method for extracting DNA from small amounts of detergent-washed clothing, and applied it to both worn and unworn, washed and unwashed cotton and polyester samples of the axillary region of T-shirts from 10 male subjects.
Section of Microbiology
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